Radiolabelled lipoproteins and method for making same

G - Physics – 01 – N

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167/48

G01N 33/60 (2006.01) A61K 51/12 (2006.01)

Patent

CA 1249513

Abstract of the Disclosure Lipoproteins radiolabelled with an isotope of technetium substantially retain their native structure and biological function. The lipoproteins can be radiolabelled by simultaneous reduction of pertechnetate and lipoprotein with sodium dithionite at pH 8-9. The resulting radiolabelled lipoproteins can be used as probes for extracorporeal imaging to analyze lipoprotein metabolism.

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