Radiolabelled particulate composition

Details Radiolabelled particulate composition Radiolabelled particulate composition

A - Human Necessities

61

K

167/101, 167/47

A61K 51/12 (2006.01)

Patent

CA 2000471

ABSTRACT The invention relates to a metal-radionuclide-labelled particulate composition which may be used in the form of a dry aerosol for lung scintigraphy, in particular, for the examination of the mucociliary transport, or for radiotherapy. The composition comprises radioactive labelled particles on a base of silica gel, another silicaceous material or a non-swelling polymer, at the surface of which organic ligands are bound covalently which comprise thiol-, amino-, alkylamino-, oxime-, dithiocarbamate-, xanthate-, thiosemicarbazone-, or dithiosemicarbazone groups or combinations thereof. The invention further relates to a method of preparing the composition and to a kit for carrying out the method.

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