Radiolabelled somatostatin receptor ligands for diagnosis...

C - Chemistry – Metallurgy – 07 – K

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C07K 14/665 (2006.01) A61K 51/08 (2006.01)

Patent

CA 2284581

The invention relates to a carrier substance for radionuclides used in the diagnosis and/or radiotherapy of somatostatin receptor-positive tumors or target cells. Said conjugate consists of somatostatin 14 agonists, lanreotide and a macrocyclic chelating agent former which forms stable chelates with metallic radionuclides in physiological conditions.

L'invention concerne une substance porteuse pour radionucléides servant au diagnostic et/ou à la radiothérapie de tumeurs positives ou de cellules cibles positives en ce qui concerne le récepteur de la somatostatine. Il s'agit d'un conjugué constitué d'agonistes de somatostatine 14 du lanréotide et d'un chélateur macrocyclique qui forme des chélates stables avec des radionucléides métalliques, dans des conditions physiologiques.

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