C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 23/00 (2006.01) A61K 31/70 (2006.01) A61K 41/00 (2006.01) A61K 51/00 (2006.01)
Patent
CA 2237263
A compound useful for in vivo imaging of organs and tumors is provided of formula (1) wherein (a) is cobalamin, (b) derived from a corrin carboxylic acid group of said cobalamin, Y is a linking group and X is a chelating group, optionally comprising a detectable radionuclide or a paramagnetic metal ion, and n is 1-3.
L'invention concerne un composé de formule (I) pouvant être utilisé pour produire des images in vivo d'organes et de tumeurs. Dans la formule, (a) représente une cobalamine; (b) est dérivé d'un groupe acide carboxylique de corrine de ladite cobalamine; Y est un groupe de liaison et X un groupe chélateur, contenant éventuellement un radionucléide détectable ou un ion métallique paramagnétique, et n est compris entre 1 et 3.
Collins Douglas A.
Hogenkamp Henricus Petrus Cornelis
Goudreau Gage Dubuc
Mayo Foundation For Medical Education And Research
The Regents Of The University Of Minnesota
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