Radionuclide metal chelates for the radiolabeling of proteins

Details Radionuclide metal chelates for the radiolabeling of proteins Radionuclide metal chelates for the radiolabeling of proteins

C - Chemistry, Metallurgy

07

K

C07K 16/30 (2006.01) A61K 51/10 (2006.01) C07C 323/00 (2006.01) C07D 263/26 (2006.01) C07D 309/08 (2006.01) C07D 327/04 (2006.01) C07F 13/00 (2006.01) C07K 1/13 (2006.01) C07K 5/06 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2031528

Chelating compounds of specified structure are useful for radiolabeling targeting proteins such as antibodies. The radiolabeled antibodies, or catabolites thereof, demonstrate improved biodistribution properties, including reduced localization within the intestines.

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