Radionuclides for medical use

Details Radionuclides for medical use Radionuclides for medical use

A - Human Necessities

61

K

A61K 51/04 (2006.01) A61K 51/10 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2570191

The use of Th-226 or mother radionuclides thereof, namely U-230 or Ac-226, in medicine is proposed. These radionuclides are particularly appropriate for the treatment of human and/or non-human mammals, in particular for therapeutic, diagnostic (detection/imaging), prophylactic and pain palliation purposes. Depending on the applications, these radionuclides may be used in various forms for treatment and/or diagnostic purposes, in particular in cationic form or in the form of radioconjugates or bone-targeting complexes. Methods of production of these radionuclides are also disclosed.

L'invention concerne l'utilisation médicale de radionucléides Th-226 ou de radionucléides-mères de Th-226, à savoir U-230 ou Ac-226. Ces radionucléides sont en particulier conçus pour traiter des mammifères humains et/ou non humains, en particulier à des fins thérapeutiques, diagnostiques (détection/imagerie), prophylactiques ou analgésiques. Selon les applications, les radionucléides peuvent être utilisés sous différentes formes à des fins thérapeutiques et/ou diagnostiques, en particulier sous forme cationique ou sous la forme de radioconjugués ou complexes de ciblage osseux. Cette invention concerne en outre des procédés de production de ces radionucléides.

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