Radiopharmaceutical and methods of synthesis and use thereof

A - Human Necessities – 61 – K

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A61K 51/04 (2006.01) C07D 221/18 (2006.01)

Patent

CA 2564005

A novel group of apomorphine derivatives are provided that are well suited as radioimaging agents upon incorporation of radionuclides. Through reaction of D ring sites, the less reactive sites of the apomorphine A ring is modified in ways previously unattainable.

L'invention concerne un nouveau groupe de dérivés d'apomorphine qui sont très appropriés en tant qu'agents de radioimagerie, suite à l'incorporation de radionucléides. Par le biais de la réaction des sites d'anneau D, les sites moins réactifs de l'anneau A d'apomorphine sont modifiés selon des manières antérieurement irréalisables.

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