Radiopharmaceutical products and their preparation procedure

Details Radiopharmaceutical products and their preparation procedure Radiopharmaceutical products and their preparation procedure

A - Human Necessities

61

K

A61K 51/06 (2006.01) A61K 51/12 (2006.01)

Patent

CA 2383517

The present invention relates to radiopharmaceutical products and their preparation procedure. These products can be used for pulmonary scintigraphy or for therapy. They comprise a polysaccharide and sequestering groups of formulae R-NH-, R-N=, and formula (I) in which R is a hydrocarbonic or aromatic group comprising at least one atom of sulphur, and R' is an atom of hydrogen or an alkyl grouping such as methyl, said sequestering groups forming a chelate type complex with a radioactive metal such as technetium.

L'invention concerne des produits radiopharmaceutiques et leur procédé de préparation. Ces produits peuvent être utilisés en scintigraphie pulmonaire ou en thérapie. Ils sont constitués d'un polysaccharide et de groupes séquestrants de formules R-NH-, R-N= et la formule (I). R est un groupe hydrocarbone ou aromatique comprenant au moins un atome de soufre. R' représente un atome d'hydrogène ou un groupement alkyle tel que méthyle. Les groupes séquestrants forment un complexe de type chélate avec un métal radioactif, par exemple le technetium.

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