C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 295/18 (2006.01) A61K 51/00 (2006.01) A61K 51/04 (2006.01) A61P 25/28 (2006.01) C07B 59/00 (2006.01) C07D 295/185 (2006.01)
Patent
CA 2424598
This invention is directed to the use of radiopharmaceuticals of formula (I) in diagnosing Alzheimer's disease. In particular the radiopharmaceuticals of the invention are able to pass through the blood-brain barrier and bind to the CCR1 receptor present in brain tissue of patients having Alzheimer's disease.
La présente invention concerne l'utilisation de produits radiopharmaceutiques de formule (I) pour le diagnostic de la maladie d'Alzheimer. En particulier, le produits radiopharmaceutiques de l'invention sont susceptibles de traverser la barrière hémato-encéphalique and se lier au récepteur du CCR1 présent dans le tissu cérébral des patients souffrant de la maladie d'Alzheimer.
Dinter Harald
Halks-Miller Meredith
Hesselgesser Joseph E.
Hilger Christoph-Stephan
Horuk Richard
Bayer Schering Pharma Aktiengesellschaft
Marks & Clerk
Schering Aktiengesellschaft
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