Radiosensitizing taxanes and their pharmaceutical preparations

Details Radiosensitizing taxanes and their pharmaceutical preparations Radiosensitizing taxanes and their pharmaceutical preparations

C - Chemistry, Metallurgy

07

D

C07D 305/14 (2006.01) A61K 31/335 (2006.01) A61K 41/00 (2006.01) A61N 5/00 (2006.01) A61N 5/10 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 407/00 (2006.01) C07D 409/00 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07F 9/655 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2231837

Taxanes containing electron-affinic radiosensitizing functional groups, their pharmaceutical preparations, and methods of making and using this new class of highly potent radiosensitizers of tumor cells.

L'invention se rapporte à des taxanes renfermant des groupes fonctionnels à effet radiosensibilisant, à affinité électronique, ainsi qu'à leurs préparations pharmaceutiques et aux procédés de fabrication et d'utilisation de cette nouvelle classe de substances qui augmentent considérablement la sensibilité des cellules tumorales aux radiations.

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