A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/00 (2006.01) A61K 51/04 (2006.01) C12Q 1/44 (2006.01)
Patent
CA 2307081
Radio-labeled compounds of the formula: (see formula I) wherein Q is (CH2)m, -CH=CH-, -CHCH3, -C(CH3)2, oxygen, sulfur or NH; X is oxygen or sulfur; Y is -(CH2)m-; L is phenyl or phenyl -(C1-C6)alkyl; wherein said phenyl is optionally substituted with (C1-C6)alkyl or halo, preferably I, F, or Br; R1 is hydrogen or (C1-C6)alkyl; m is an integer from 1 to 3; and pharmaceutically acceptable salts thereof into the bloodstream of a human; are useful as in vivo imaging agents for diagnosis of Alzheimer's disease.
Bencherif Badreddine
Dannals Robert F.
Frost J. James
Musachio John
Scheffel Ursula
Pfizer Products Inc.
Smart & Biggar
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