A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 51/12 (2006.01) G21G 1/06 (2006.01)
Patent
CA 2564895
The present invention refers to a method for producing a radium target for the production of radionuclides by means of accelerated protons, whereby at least one radium containing material out of an aqueous-organic solution or suspension of such a material is applied by means of a dispersing device on a surface in such a way that the dispersing device and the surface are moving relatively towards each other and that the solvent is removed substantially spontaneously. Further, the invention refers to a radium target that is created in such a way that it may exhibit an activity of up to 1.5 curie. The radium targets according to the present invention serve for the production of the radionuclide 225 Ac, which may be used in nuclear medicine in the treatment of cancer, particularly in form of its daughter nuclide 213Bi.
L'invention concerne un procédé de production d'une cible de radium destinée à la production de radionucléides, au moyen de protons accélérés. Au moins un matériau contenant du radium, extrait d'une solution organique aqueuse ou d'une suspension dudit matériau, est appliqué au moyen d'un dispositif de dispersion sur une surface, de façon à déplacer relativement le dispositif de dispersion et la surface l'un vers l'autre, et à éliminer le solvant de manière sensiblement spontanée. L'invention concerne en outre une cible de radium créée de sorte qu'elle présente une activité pouvant atteindre 1,5 curie. Les cibles de radium de l'invention servent à la production du radionucléide ?225 ¿Ac, qui peut être utilisé en médecine nucléaire pour le traitement de cancers, en particulier sous la forme de son radionucléide de filiation?213¿Bi.
Harfensteller Mark
Huenges Ernst
Moreno Bermudez Josue Manuel
Schilp Michael
Actinium Pharmaceuticals Inc.
Borden Ladner Gervais Llp
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