Raf inhibitors for the treatment of thyroid cancer

Details Raf inhibitors for the treatment of thyroid cancer Raf inhibitors for the treatment of thyroid cancer

A - Human Necessities

61

K

A61K 31/4439 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2686787

The invention relates to the use of an Raf inhibitor for the manufacture of pharmaceutical compositions for the treatment of thyroid cancer, more specifically papillary thyroid cancer (PTC); the use of a Raf inhibitor in the treatment of thyroid cancer, more specifically PTC; a method of treating warm-blooded animals including mammals, especially humans, suffering from thyroid cancer, more specifically PTC, by administering to a said animal in need of such treatment a dose effective against said disease of an Raf inhibitor. The invention also relates to the use of a Raf inhibitor in combination with a platin compound for the treatment of thyroid cancer, more specifically papillary thyroid cancer.

L'invention concerne l'utilisation d'un inhibiteur de Raf pour la fabrication d'une composition pharmaceutique pour le traitement du cancer de la thyroïde, plus spécifiquement pour le cancer de la thyroïde papillaire (PTC) ; l'utilisation d'un inhibiteur de Raf dans le traitement du cancer de la thyroïde, plus spécifiquement du PTC ; un procédé de traitement d'animaux à sang chaud comprenant des mammifères, spécialement les êtres humains, souffrant du cancer de la thyroïde, plus spécifiquement du PTC, par administration audit animal en besoin d'un tel traitement d'une dose efficace vis-à-vis de ladite maladie d'un inhibiteur de Raf. L'invention concerne également l'utilisation d'un inhibiteur de Raf en combinaison avec un composé de platine pour le traitement du cancer de la thyroïde, du cancer de la thyroïde papillaire.

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