C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/47 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2469263
The invention provides novel means to inhibit the Mitogen Activated Protein Kinases (MAPKs) pathway activated by Ras/Raf complex using GILZ protein related compounds as inhibitors of Raf/Ras-mediated signal transduction. Pharmaceutical compositions containing such compounds are also disclosed.
L'invention concerne de nouveaux moyens d'inhiber la voie de protéines kinases activées par des agents mitogènes (MAPK), activés par un complexe Ras/Raf au moyen d'une protéine GILZ associée à des composés, en tant qu'inhibiteurs d'une transduction de signal médié par Raf/Ras. L'invention concerne également des compositions contenant de tels composés.
Applied Research Systems Ars Holding N.v.
Kirby Eades Gale Baker
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