Rage/diaphanous interaction and related compositions and...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12N 15/63 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2601630

This invention provides a polypeptide consisting essentially of all or a portion of the cytoplasmic domain of RAGE. This invention further provides a polypeptide consisting essentially of a portion of Diaphanous that binds to the cytoplasmic domain of RAGE. Additionally, this invention provides related nucleic acids, vectors, cells and methods.

Cette invention concerne un polypeptide composé essentiellement de tout ou partie du domaine cytoplasmique de RAGE. Cette invention concerne également un polypeptide composé essentiellement d'une partie d'un Diaphane qui se lie au domaine cytoplasmique de RAGE. Cette invention concerne en outre des acides nucléiques, des vecteurs, des cellules et des méthodes associés.

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