Rage-related methods and compositions for treating...

A - Human Necessities – 61 – K

Patent

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A61K 39/395 (2006.01) A61K 38/17 (2006.01) A61P 13/00 (2006.01)

Patent

CA 2536512

This invention provides methods, compositions and articles of manufacture for inhibiting the onset of and treating glomerular injury. The instant invention is based on the blockade of RAGE and/or RAGE G82S function.

La présente invention a trait à de procédés, des compositions et des articles de fabrication pour l'inhibition de l'apparition et le traitement de la lésion glomérulaire. La présente invention est basée sur le blocage de la fonction de récepteur des produits terminaux de la glycation avancée et/ou de récepteur de la fonction des produits terminaux de la glycation avancée G82S.

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