Rage tumor rejection antigens

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 35/14 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01) A61K 38/00 (2006.01) C12N 5/08 (2006.01)

Patent

CA 2211448

The invention describes the RAGE tumor rejection antigen precursor family, including nucleic acids encoding such tumor rejection antigen precursors, tumor rejection antigen peptides or precursors thereof and antibodies relating thereto. Methods and products also are provided for diagnosing and treating conditions characterized by expression of a RAGE tumor rejection antigen precursor.

Cette invention décrit la famille RAGE des précurseurs d'antigènes de rejet de tumeurs, et elle décrit, entre autres, les acides nucléiques codant de tels précurseurs d'antigènes de rejet de tumeurs, des peptides d'antigènes de rejet de tumeurs ou des précurseurs de tels peptides ainsi que les anticorps associés. L'invention concerne également des procédés et des produits permettant le diagnostic et le traitement d'états caractérisés par l'expression d'un précurseur d'antigène de rejet de tumeurs de la famille RAGE.

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