Random array dna analysis by hybridization

C - Chemistry – Metallurgy – 12 – Q

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C12Q 1/68 (2006.01) C07H 21/04 (2006.01) C12P 19/34 (2006.01)

Patent

CA 2555962

The invention relates to methods and devices for analyzing single molecules, i.e. nucleic acids. Such single molecules may be derived from natural samples, such as cells, tissues, soil, air and water without separating or enriching individual components. In certain aspects of the invention, the methods and devices are useful in performing nucleic acid sequence analysis by probe hybridization.

L'invention concerne des procédés et des dispositifs permettant d'analyser des molécules uniques, à savoir des acides nucléiques. Ces molécules uniques peuvent être dérivées d'échantillons naturels, tels que des cellules, des tissus, le sol, l'air et l'eau, sans que des composants individuels ne soient isolés ou enrichis. Dans certains modes de réalisation de la présente invention, les procédés et dispositifs servent à effectuer une analyse de séquence d'acides nucléiques par hybridation de sondes.

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