C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/12 (2006.01) A61K 38/17 (2006.01) C07K 14/705 (2006.01) C12Q 1/42 (2006.01) C12Q 1/48 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2463649
The present invention provides non-naturally occurring proteins that bind to RANK and polynucleotides encoding the same. The proteins of the invention can be used for enhancing bone formation by either inhibiting bone resorption or inducing osteogenesis.
L'invention concerne des protéines d'origine non naturelle qui se lient à RANK, ainsi que des polynucléotides codant pour celles-ci. Les protéines de cette invention peuvent être utilisées pour améliorer la formation osseuse soit en empêchant la résorption osseuse soit en induisant l'ostéogenèse.
Lam Jonathan
Ross F. Patrick
Teitelbaum Steven L.
Barnes-Jewish Hospital
Lam Jonathan
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Ross F. Patrick
Teitelbaum Steven L.
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