Rantes mutants and therapeutic applications thereof

Details Rantes mutants and therapeutic applications thereof Rantes mutants and therapeutic applications thereof

C - Chemistry, Metallurgy

07

K

C07K 14/52 (2006.01) A61K 38/19 (2006.01) C12N 15/19 (2006.01)

Patent

CA 2316447

RANTES mutants characterised by the substitution or addition of amino acids at the N-terminal of RANTES wild-type sequence and in the N-loop and/or 40's loop regions of RANTES wild-type sequence, and their use as anti-HIV, anti-allergic or anti-inflammatory agents.

L'invention concerne des mutants RANTES caractérisés par la substitution ou l'addition d'acides aminés à l'extrémité N-terminale de la séquence RANTES sauvage et dans les régions de la boucle N et/ou de la boucle 40 de la séquence RANTES sauvage; ainsi que leur utilisation comme agents anti-VIH, anti-allergiques ou anti-inflammatoires.

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