Rantes peptide and fragments and compositions comprising it...

Details Rantes peptide and fragments and compositions comprising it... Rantes peptide and fragments and compositions comprising it...

C - Chemistry, Metallurgy

12

N

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2207036

Modifications to RANTES can result in the modified polypeptide acting as a RANTES or MIP-1.alpha. antagonist. Such antagonists can be used in therapy to reduce inflammation. They are also useful in studying the properties of RANTES or of MIP-1.alpha..

Des modifications de la protéine RANTES peuvent résulter en un polypeptide modifié agissant comme un antagoniste de RANTES ou de MIP-1.alpha.. On peut utiliser de tels antagonistes en thérapie afin de réduire l'inflammation. Ces antagonistes sont également utiles dans l'étude des propriétés de RANTES ou de MIP-1.alpha..

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