C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 498/18 (2006.01) A61K 31/436 (2006.01) A61K 35/00 (2006.01) A61P 25/16 (2006.01) A61P 29/00 (2006.01) C07D 498/22 (2006.01)
Patent
CA 2590155
The present invention provides compounds of the following structure, wherein R1, R2, R4, R4~, R6, R7, and R15 are defined above: These compounds are useful in treating neurological disorders or complications due to stroke or head injury; benign or malignant neoplastic disease, carcinomas and adenocarcinomas; proliferative disorders; and inflammatory disorders. The compounds are therefore useful as neuroprotective and neurogenerative, anti- proliferative, and anti-inflammatory agents.
L'invention concerne des composés ayant la structure ci-après, sachant que R1, R2, R4, R4', R6, R7, et R15 sont tels que définis dans la description. Ces composés sont utiles pour traiter les troubles neurologiques ou les complications dues aux troubles suivants : accident vasculaire cérébral ou traumatisme crânien ; maladie néoplasique bénigne ou maligne, carcinomes et adénocarcinomes; troubles prolifératifs ; et troubles inflammatoires. Ces composés sont donc utiles comme agents neuroprotecteurs et neurorégénérateurs, antiprolifératifs et anti-inflammatoires.
Graziani Edmund Idris
Pong Kevin
Skotnicki Jerauld
Torys Llp
Wyeth
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