Rapamycin assay

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/18 (2006.01) A61K 39/385 (2006.01) C07H 19/01 (2006.01) C07K 16/12 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2156397

Monoclonal antibodies to rapamycin and to 40-O-alkylated derivatives of rapamycin are provided, together with novel haptens, immunogenic conjugates, and processes for making them and assay kits for using them. Rapamycin has known pharmaceutical applications, in particular, as an immunosuppressant. The assay kits of the present invention can be used for monitoring blood levels of rapamycin.

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