Rapamycin formulation for iv injection

Details Rapamycin formulation for iv injection Rapamycin formulation for iv injection

A - Human Necessities

61

K

A61K 47/32 (2006.01) A61K 9/08 (2006.01) A61K 31/33 (2006.01) A61K 31/365 (2006.01) A61K 31/395 (2006.01) A61K 31/435 (2006.01) A61K 31/445 (2006.01) A61K 35/74 (2006.01) A61K 47/10 (2006.01) A61P 37/06 (2006.01) C07D 498/12 (2006.01) A61K 31/71 (1990.01)

Patent

CA 2133180

ABSTRACT RAPAMYCIN FORMULATION FOR IV INJECTION Disclosed herein is an aqueous, injectable rapamycin solution comprising 40 to 75 volume percent of a concentrate solution of rapamycin in propylene glycol, atconcentrations of rapamycin ranging from 0.25 mg/ml to 8 mg/ml, in combination with a diluent solution comprising water, wherein the diluent comprises 60 to 25 volume percent of the combined solution and the concentration of rapamycin in the combined solution ranges from 0.1mg/ml to 4 mg/ml.

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