Rapid absorption selective 5-ht agonist formulations

Details Rapid absorption selective 5-ht agonist formulations Rapid absorption selective 5-ht agonist formulations

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/20 (2006.01) A61K 31/4045 (2006.01)

Patent

CA 2514875

The invention provides for a rapid absorption pharmaceutical composition comprising an effective amount of at least one selective 5-HT agonist, at least one spheronization aid and at least one solubility enhancer. The composition of the invention is incorporated into microparticles, which may be subsequently taste-masked and incorporated into a variety of dosage forms for administration to a patient suffering from migraine.

L'invention porte sur une composition pharmaceutique à absorption rapide qui comprend une quantité efficace d'au moins un agoniste 5-HT sélectif, au moins un support de sphéronisation et au moins un activateur de solubilité. La composition de l'invention est incorporée dans des microparticules dont la saveur peut être ensuite masquée et est incorporée dans diverses formes galéniques en vue d'être administrée à un patient souffrant de migraine.

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