C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 9/16 (2006.01) C12N 9/22 (2006.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01) C12Q 1/70 (2006.01)
Patent
CA 2203627
The present invention relates to means for cleaving a nucleic acid cleavage structure in a site-specific manner. Enzymes, including 5' nucleases and 3' exonucleases, are used to screen for known and unknown mutations, including single base changes, in nucleic acids. Methods are provided which allow for the identification of genetic mutations in human gene sequences, including the human p53 gene, in a sample. Methods are provided which allow for the detection and identification of bacterial and viral pathogens and species in a sample.
L'invention porte sur des moyens de segmentation de structures de clivage d'acide nucléique d'une manière propre à un site. On utilise des enzymes, dont des 5' nucléases et des 3' exonucléases, pour dépister les mutations connues et inconnues y compris les mutations de la base unique des acides nucléiques. L'invention porte également sur des méthodes d'identification dans des échantillons de mutation génétiques dans des séquences de gènes humains y compris le gène humain p53, et sur des méthodes de détection et d'identification dans des échantillons d'espèces et d'agents pathogènes bactériens et viraux.
Brow Mary Ann D.
Dahlberg James E.
Fors Lance
Heisler Laura M.
Lyamichev Victor I.
Smart & Biggar
Third Wave Technologies Inc.
LandOfFree
Rapid detection and identification of nucleic acid variants... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rapid detection and identification of nucleic acid variants..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rapid detection and identification of nucleic acid variants... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1387330