C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C12N 9/08 (2006.01)
Patent
CA 2134103
2134103 9322454 PCTABS00027 Multidrug resistant strains of Mycobacterium tuberculosis represent a considerable threat to public health worldwide. Resistance to isoniazid (INH), rifampicin or analogues thereof, or streptomycin, i.e. key components of anti-tuberculosis regimens, need frequently to be detected. The invention involves the detection of a mutation in either the katG gene (isoniazid resistance), the rpoB gene (rifampicin resistance) or rpsL gene (streptomycin resistance).
Bodmer Thomas
Cole Stewart
Heym Beate
Honore Nadine
Telenti Amalio
Assistance Publique - Hopitaux de Paris
Gowling Lafleur Henderson Llp
Institut Pasteur
Medical Research Council
Universite de Berne
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