Rapid inducible beta-lactamase screen test

Details Rapid inducible beta-lactamase screen test Rapid inducible beta-lactamase screen test

C - Chemistry, Metallurgy

12

Q

C12Q 1/34 (2006.01) C12Q 1/18 (2006.01) C12Q 1/20 (2006.01)

Patent

CA 2086507

2086507 9219763 PCTABS00017 In an assay for determination of beta-lactam antibiotic resistance in a target bacterial strain, the strain is grown in the presence of both a beta-lactamase inducing antibiotic and a beta-lactam indicator antibiotic which kills or inhibits the growth of bacteria unable to hydrolyze beta-lactam antibiotics. Growth, indicative of drug resistance in the target strain, is monitored by detecting a fluorophor released by the enzymatic cleavage of a metabolizable fluorogenic compound.

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