Rapid method of determining clearance of prion protein

Details Rapid method of determining clearance of prion protein Rapid method of determining clearance of prion protein

G - Physics

01

N

G01N 33/569 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2262066

The invention provides a rapid, sensitive immunoassay capable of detecting and quantitating pathogenic protein to a level of 3 to 5 logs. The preferred immunoassay utilized is a chemiluminescent endpoint for a Western blot immunoassay. The invention has been successfully applied to track the clearance of pathogenic protein during production of proteins derived from plasma, It is particularly applicable and has been confirmed by bioassay to relate TSE infectivity to quantitative results on prion protein

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