C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) C12Q 1/70 (2006.01) G01B 7/14 (2006.01) G01L 5/00 (2006.01) G01N 27/72 (2006.01)
Patent
CA 2160031
A method for determining a DNA or RNA sequence, comprising determining the pairing or separating energy between each base pair of the DNA or a double-stranded RNA/DNA hybrid corresponding to the DNA or RNA sequence to be determined, and comparing said energy with predetermined values.
La présente invention con- cerne un procédé de détermination d'une séquence d'ADN ou d'ARN, caractérisé en ce qu'on détermine l'énergie d'appariement ou de desappariement entre chaque paire de base de l'ADN ou d'un hybride ARN/ADN double brin correspondant à la séquence d'ADN ou d'ARN à déterminer et en ce que l'on compare cette énergie à des valeurs prédéterminées.
Bensimon Aaron
Bensimon David
Chiffaudel Arnaud
Croquette Vincent
Centre National de La Recherche Scientifique (c.n.r.s.)
Institut Pasteur
Robic
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