Rapid production of biological products by fermentation in a...

C - Chemistry – Metallurgy – 12 – M

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C12M 1/00 (2006.01) C12N 1/00 (2006.01) C12P 1/00 (2006.01) C12M 3/00 (2006.01) C12N 1/20 (2006.01) C12P 7/56 (2006.01)

Patent

CA 1225610

ABSTRACT A method and apparatus is provided for continuous, cultivation of microbial, animal or plant cells, particularly bacteria for producing lactic acid, employing a reactor comprising at least two microporous walled hollow fibers having an open port at one end and a sealed port at the other end. The mass transfer of nutrients to the cells in the reactor shell space and of products from the cells is enhanced by convective currents between the first and second fibers which result in attainment of improved cell density and productivity of desirable cell products.

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