Rapid setting calcium phosphate cements

A - Human Necessities – 61 – K

Patent

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Details

A61K 9/00 (2006.01) A61F 2/00 (2006.01) A61K 9/14 (2006.01) A61K 31/695 (2006.01) A61K 33/06 (2006.01) A61K 33/42 (2006.01)

Patent

CA 2567329

Methods are provided for producing compositions, e.g. pastes or clays, which rapidly set into high-strength calcium phosphate products. In the subject methods, dry reactants that include calcium and phosphate sources, as well as a monovalent cation dihydrogen phosphate salt, are combined with a setting fluid and the combined reactants are mixed to produce the settable composition. A feature of the invention is that cements rapidly set into high strength product compositions. Also provided are the compositions themselves as well as kits for preparing the same. The subject methods and compositions produced thereby find use in a variety of applications, including hard tissue repair applications.

L'invention porte sur des procédés d'obtention de compositions, pâteuses ou argileuses, à prise rapide donnant des produits de phosphate de calcium de haute dureté. Lesdits procédés consistent à combiner des réactifs secs incluant des sources de calcium et de phosphate et un sel monovalent de cations de dihydrogène phosphate avec un fluide de prise, puis à les mélanger pour obtenir des compositions à prise rapide donnant des produits de phosphate de calcium de haute dureté. L'invention porte également sur les compositions elles-mêmes et sur leurs trousses de préparation. Lesdits procédés, et compositions ont de nombreuses applications dont la réparation des tissus durs.

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