Rapidly disintegrating dosage form for releasing active...

Details Rapidly disintegrating dosage form for releasing active... Rapidly disintegrating dosage form for releasing active...

A - Human Necessities

61

K

A61K 9/70 (2006.01) A61K 9/00 (2006.01)

Patent

CA 2414665

A dosage form which is, in particular, sheet-like and rapidly disintegrating or soluble in an aqueous environment for rapid release of active ingredients in the oral cavity, in body orifices or in body cavities, where the dosage form comprises a matrix which comprises one or more water--soluble polymers as base substances, and comprises at least one active ingredient, is characterized in that the dosage form is provided with spaces or cavities which are present in the polymeric matrix and whose contents differ in terms of the state of aggregation from the matrix.

L'invention concerne une forme d'administration en particulier plate, se décomposant ou se dissolvant rapidement dans un environnement aqueux, pour la libération rapide de principes actifs dans la cavité buccale, dans des ouvertures corporelles ou dans des cavités corporelles. Cette forme d'administration comprend une matrice qui contient au moins un polymère hydrosoluble comme substance de base, et au moins un principe actif, et elle se caractérise en ce que sa matrice polymère comporte des chambres ou des cavités dont le contenu diffère en ce qui concerne l'état d'agrégation de la matrice.

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