A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 31/00 (2006.01)
Patent
CA 2687310
A tablet for insertion into a vagina including 0.01 to 500 mg of a vaginal medication, such as a microbicide, such as cellulose acetate 1,2- benzenedicarboxylate (CAP); 100 to 500 mg of mannitol powder; 50 to 300 mg of inert microcrystalline cellulose; 10 to 80 mg of hydroxypropyl methylcellulose; 50 to 250 mg of glycerol and optionally 2 to 4 mg of at least one preservative which protects against microbicidal contamination and discourages the growth of yeast in the vagina. The tablet which includes CAP as the vaginal medication is vaginally administered before coitus in methods for preventing the sexual transmission of HIV- 1, HIV-2, herpesvirus, or an infection caused by Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Haemophilus ducreyi or Treponema pallidum. The tablet which includes CAP as the vaginal medication is vaginally administered to prevent or treat bacterial vaginosis.
L'invention concerne un comprimé pour insertion dans le vagin comprenant de 0,01 à 500 mg d'une médication vaginale, telle qu'un microbiocide, tel que l'acétate 1,2-benzènedicarboxylate de cellulose (CAP); 100 à 500 mg de poudre de mannitol; 50 à 300 mg de cellulose microcristalline inerte; 10 à 80 mg d'hydroxypropyle méthylcellulose; 50 à 250 mg de glycérol et facultativement 2 à 4 mg d'au moins un conservateur qui assure une protection contre une contamination microbiocide et décourage la croissance de levure dans le vagin. Le comprimé qui comprend du CAP comme médication vaginale est administré par voie vaginale avant un coït dans des procédés pour prévenir la transmission sexuelle du VIH-1, du VIH-2, du virus de l'herpès ou d'une infection causée par Neisseria gonorrhoeae, Chlamydia trachomatis, Trichomonas vaginalis, Haemophilus ducreyi ou Treponema pallidum. Le comprimé qui comprend du CAP comme médication vaginale est administré par voie vaginale pour empêcher ou traiter une vaginose bactérienne.
Neurath Alexander Robert
Stone Alan
Strick Nathan
New York Blood Center Inc.
Smart & Biggar
LandOfFree
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