C - Chemistry – Metallurgy – 12 – Q
Patent
C - Chemistry, Metallurgy
12
Q
C12Q 1/68 (2006.01) A61K 31/35 (2006.01) A61K 31/351 (2006.01) A61K 31/455 (2006.01) G01N 33/566 (2006.01)
Patent
CA 2219028
Retinoid compounds which repress expression of the gene promoted by AP1 protein but which do not significantly activate expression of the genes having RA-responsive elements in their promoter region through RAR.alpha. and RAR.GAMMA. receptor subtypes, are used, with reduced side effects, for treating diseases and conditions which are responsive to therapy with retinoids.
On peut traiter, avec peu d'effets secondaires, des maladies et états pathologiques réagissant bien à la thérapie aux rétinoïdes, en utilisant des composés de rétinoïdes ayant la propriété d'inhiber l'expression de gènes induite par la protéine AP1 sans activer de manière significative, par l'intermédiaire de sous-types de récepteurs RAR.alpha. et RAR.GAMMA., l'expression de gènes comportant des éléments sensibles à RA dans leur région promotrice.
Athanikar Jyoti
Chandraratna Roshantha A.
Nagpal Sunil
Song Tae K.
Vuligonda Vidyasagar
Allergan
Allergan Inc.
Gowling Lafleur Henderson Llp
LandOfFree
Rar.beta. selective retinoid compounds for inhibiting gene... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Rar.beta. selective retinoid compounds for inhibiting gene..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Rar.beta. selective retinoid compounds for inhibiting gene... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-2048324