Ras activator nucleic acid molecules - guanine nucleotide...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/12 (2006.01) C07K 14/47 (2006.01)

Patent

CA 2360770

The invention is a Guanine Releasing Factor, GRF4 nucleic acid molecule and its corresponding protein which has an important role in cell signaling. The invention also includes biologically functional equivalent nucleic acid molecules and proteins. The invention also relates to methods of using these nucleic acid sequences and proteins in medical treatments and drug screening.

L'invention concerne une molécule d'acides nucléiques GRF4 et la protéine correspondante dont le rôle de signalisation de cellules est important. L'invention traite également de molécules d'acides nucléiques et de protéines équivalentes biologiquement fonctionnelles. Elle concerne enfin des techniques d'emploi de ces séquences d'acides nucléiques et protéines dans des traitements médicaux et criblages de médicaments.

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