Ras activator nucleic acid molecules, proteins and methods...

Details Ras activator nucleic acid molecules, proteins and methods... Ras activator nucleic acid molecules, proteins and methods...

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 48/00 (2006.01) C07K 14/47 (2006.01) C07K 14/705 (2006.01) C07K 14/82 (2006.01) C07K 16/28 (2006.01) C07K 16/32 (2006.01)

Patent

CA 2259830

The invention is a RasGRF4 nucleic acid molecule and its corresponding protein which has an important role in cell signaling. This protein is regulated by Nedd4, which regulates protein stability, PDZ, which localizes the protein, and cNMP which activates it. The invention also includes biologically functional equivalent nucleic acid molecules and proteins. The invention also relates to methods of using these nucleic acid sequences and proteins in medical treatments and drug screening.

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