Ras farnesyl transferase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 243/14 (2006.01) A61K 31/55 (2006.01) A61K 31/58 (2006.01) C07D 223/16 (2006.01) C07D 243/10 (2006.01) C07D 243/24 (2006.01) C07D 401/00 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/00 (2006.01) C07D 403/06 (2006.01) C07D 403/10 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/06 (2006.01) C07D 409/00 (2006.01) C07D 409/14 (2006.01) C07D 413/00 (2006.01) C07D 417/00 (2006.01) C07D 487/02 (2006.01) C07D 487/04 (2006.01) C07D 498/04 (2006.01) C07D 513/04 (2006.01) C07F 9/6

Patent

CA 2160786

Benzodiazepine derivatives are disclosed that act as potent inhibitors of ras farnesyl:protein transferase. Pharmaceutical compositions containing these benzodiazepines are provided for treatment of diseases for which inhibition of the ras farnesyl:protein transferase is indicated.

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