Ras mutation and compositions and methods related thereto

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/12 (2006.01) A61K 31/7088 (2006.01) A61K 38/16 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 1/00 (2006.01) C07K 14/47 (2006.01) C07K 14/82 (2006.01) C07K 19/00 (2006.01) C12N 1/19 (2006.01) C12N 9/22 (2006.01) C12N 15/11 (2006.01) C12N 15/62 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/574 (2006.01) C07H 21/00 (2006.01)

Patent

CA 2647102

Disclosed are newly discovered Ras mutations and combinations of mutations, proteins and peptides and fusion proteins containing these mutations, nucleic acid molecules encoding such proteins, peptides, and fusion proteins, and a variety of tools and diagnostic, therapeutic, and screening methods associated with the use of such mutations.

L'invention concerne de nouvelles mutations de Ras et des combinaisons de mutations, des protéines, des peptides et des protéines de fusion contenant ces mutations, des molécules d'acide nucléique codant pour lesdites protéines, peptides et protéines de fusion, ainsi qu'une diversité d'outils et des méthodes diagnostiques, thérapeutiques et de criblage associées à l'utilisation desdites mutations.

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