Rat st38.2 chemokine

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) C07K 16/24 (2006.01) C07K 19/00 (2006.01) C12N 5/08 (2006.01) C12N 5/10 (2006.01) C12Q 1/68 (2006.01) G01N 33/50 (2006.01) G01N 33/53 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2287876

The present invention relates to the discovery of genes and proteins, which function in pathways involved in brain pathogenesis. In particular, the genes and proteins relate to inflammatory tissue responses caused by brain injuries such as trauma, ischemia or autoimmune-inflammation or other diseases or processes related to neuroinflammation. The compounds disclosed in the present invention are useful as therapeutics, diagnostics and in screening assays.

L'invention concerne la découverte de gènes et de protéines, qui fonctionnent dans les voies impliquées dans la pathogénèse du cerveau. En particulier, les gènes et les protéines concernent les réponses inflammatoires des tissus provoquées par des blessures du cerveau telles que des traumas, l'ischémie ou l'inflammation auto-immune ou autres maladies ou procédés concernés par l'inflammation des neurones. Les composés selon la présente invention sont des outils thérapeutiques et diagnostiques utiles, et présentent également un rôle important dans les criblages.

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