Rate-controlled transdermal administration of risperidone

A - Human Necessities – 61 – K

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Details

A61K 31/505 (2006.01) A61K 9/70 (2006.01) A61K 31/519 (2006.01)

Patent

CA 2214420

Medical patches for the rate-controlled transdermal administration of risperidone through intact skin for an extended period of time which comprise: (a) a drug reservoir (1) comprising risperidone (I) and a skin permeation enhancer (II) for risperidone in amounts sufficient to deliver (I) at a therapeutically effective rate for said extended period of time, and (b) a drug-impermeable backing (2); methods of treating patients with such patches; process of manufacturing such patches.

Timbre permettant l'administration transdermique à vitesse de diffusion régulée de rispéridone à travers la peau intacte pendant un temps prolongé, constitué: a) par un réservoir de médicament (1) contenant de la rispéridone (I) et une substance de renforcement de la perméativité de la peau (II) pour l'administration de rispéridone (I) dans des quantités suffisantes à une vitesse de diffusion thérapeutiquement efficace pendant le temps prolongé indiqué, et b) par un support imperméable aux substances médicamenteuses (2); méthodes de traitement des patients à l'aide de ces timbres et procédé de fabrication de ces timbres.

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