C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/60 (2006.01) A61K 38/51 (2006.01) C08B 37/10 (2006.01) C12N 9/88 (2006.01) C12N 11/00 (2006.01) C12S 3/02 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2235223
Modified heparinases having altered binding specificity and activity are provided. Isolated nucleic acids encoding the same as well as vectors and host cells are provided. Methods for using the modified heparinases are also provided.
Héparinases modifiées présentant une spécificité de liaison et une activité modifiées. L'invention porte également sur des acides nucléiques isolés codant ces héparinases ainsi que sur des vecteurs et des cellules hôtes de celles-ci. L'invention porte enfin sur des méthodes d'utilisation de telles héparinases modifiées.
Cooney Charles L.
Ernst Steffen
Godavarti Ranganathan
Langer Robert
Sasisekharan Ramnath
Massachusetts Institute Of Technology
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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