Ratios of collagen peptides, their uses and products

A - Human Necessities – 61 – K

Patent

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A61K 49/00 (2006.01) C12Q 1/00 (2006.01)

Patent

CA 2500670

The present invention provides a ratio of two collagen-derived peptides which can be used to track the progression of joint destruction in osteoarthritis and rheumatoid arthritis or any destructive arthritis. In addition, the ratio can be used to screen for agents to treat osteoarthritis and rheumatoid arthritis. Furthermore, it can also be used to monitor efficacy of current therapeutic regimens and determine the type of therapy that should be used to treat the arthritis (aggressive versus non~aggressive).

L'invention porte sur le rapport entre deux peptides dérivant de collagènes pouvant servir à suivre la progression de la destruction des articulations dans l'ostéoarthrite, la polyarthrite rhumatoïde et toute arthrite destructrice. Ledit rapport peut en outre servir au criblage d'agents traitant l'ostéoarthrite et la polyarthrite rhumatoïde, à vérifier l'efficacité de régimes thérapeutiques en cours, et à déterminer le type de thérapie (agressive ou non agressive) à retenir pour traiter les arthrites.

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