Rbm3 as a marker for breast cancer prognosis

G - Physics – 01 – N

Patent

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G01N 33/574 (2006.01)

Patent

CA 2710511

The present invention provides means, such as a method, for determining whether a prognosis for a mammalian subject having a breast cancer is better than a reference prognosis. The method comprises the steps of: providing a sample earlier obtained from the subject; evaluating the amount of RBM3 protein present in at least part of said sample, and determining a sample value corresponding to said evaluated amount; comparing the sample value obtained with a reference value associated with said reference prognosis; and, if said sample value is higher than said reference value, concluding that the prognosis for said subject is better than said reference prognosis.

Linvention concerne un moyen, tel quun procédé, pour déterminer si un pronostic de cancer du sein chez un sujet mammifère est meilleur quun pronostic de référence. Le procédé comprend les étapes suivantes : la fourniture dun échantillon obtenu du sujet antérieurement ; lévaluation de la quantité de protéine RBM3 présente dans au moins une partie dudit échantillon, et la détermination dune valeur déchantillon correspondant à ladite quantité évaluée ; la comparaison de la valeur déchantillon obtenue avec une valeur de référence associée audit pronostic de référence ; et, si ladite valeur déchantillon est supérieure à ladite valeur de référence, la conclusion que le pronostic pour ledit sujet est meilleur que ledit pronostic de référence.

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