Reagent and method for attaching target molecules to a surface

Details Reagent and method for attaching target molecules to a surface Reagent and method for attaching target molecules to a surface

C - Chemistry, Metallurgy

07

H

C07H 21/00 (2006.01) C07B 61/00 (2006.01) C07C 45/63 (2006.01) C07C 235/84 (2006.01) C07C 323/42 (2006.01) C07H 1/08 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2304362

Method and reagent composition for covalent attachement of target molecules, such as nucleic acids, onto the surface of a substrate. The reagent composition includes groups capable of attracting the target molecule as well as groups capable of covalently binding to the target molecule, once attracted. Optionally, the composition can contain photoreactive groups for use in attaching the reagent composition to the surface.

On décrit un procédé et une composition de réactif utiles pour attacher par covalence des molécules cibles, telles que des acides nucléiques sur la surface d'un substrat. La composition de réactif comprend des groupes capables d'attirer la molécule cible ainsi que des groupes capables de se lier par covalence à la molécule cible lorsqu'elle est attirée. La composition peut facultativement contenir des groupes photoréactifs utiles pour fixer la composition de réactif sur la surface.

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