Reagent delivery apparatus and methods

G - Physics – 01 – N

Patent

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Details

G01N 1/28 (2006.01) B01L 99/00 (2010.01)

Patent

CA 2569314

Apparatus for dispensing droplets of reagent onto samples includes a probe tip to which droplets of reagent can adhere. The apparatus advances the probe tip toward a sample until a droplet of reagent touches the sample and is pulled off from the probe tip. A sensor detects that the droplet has been pulled off from the probe tip and halts the advance of the probe tip before the probe tip touches the sample. Such apparatus may be used to automatically dispense small volumes of reagent onto fragile samples.

La présente invention a trait à un appareil pour la distribution de gouttelettes de réactif sur des échantillons comportant une pointe de sonde à laquelle les gouttelettes peuvent adhérer. L'appareil déplace vers l'avant la pointe de sonde vers un échantillon jusqu'au contact entre une gouttelette de réactif et l'échantillon et sa chute à partir de la pointe de sonde. Un capteur assure la détection de la chute de la gouttelette à partir de la pointe de sonde et arrête le déplacement vers l'avant de la pointe de sonde avant le contact entre la pointe de sonde et l'échantillon. Un tel appareil peut être utilisé pour la distribution automatique de faibles volumes de réactif sur des échantillons fragiles.

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