C - Chemistry – Metallurgy – 12 – P
Patent
C - Chemistry, Metallurgy
12
P
C12P 19/34 (2006.01) C12N 9/12 (2006.01) C12N 15/10 (2006.01) C12Q 1/68 (2006.01)
Patent
CA 2413669
The present invention is directed to the use of a poly-hydroxy-aryl-poly-acid with 3-6 ortho-hydroxy-acid moieties as an additive for a nucleic acid amplification reaction. Surprisingly, such an addition results in prevention of nonspecific primer dimer formation and thus in a more specific and sensitive PCR.
Birkner Christian
Heindl Dieter
von Der Eltz Herbert
F. Hoffmann-La Roche Ag
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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