Reagents for use in binding assays to determine valproic acid

C - Chemistry – Metallurgy – 07 – H

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167/139, 530/15.

C07H 17/07 (2006.01) C07K 16/44 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1152492

ABSTRACT OF THE DISCLOSURE Reagents for use in binding assays, particularly immunoassays, to determine valproic acid in liquid media such as serum. Such reagents include antibody to val- proic acid and .beta.-galactosyl-umbelliferone-valproic acid conjugates. Also provided are compounds used to prepare such reagents, including valproic acid immunogen conju- gates and intermediates in the synthesis of such immunogen conjugates and .beta.-galactosyl-umbelliferone-labeled conjugates.

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