Reagents that facilitate the purification of compounds...

Details Reagents that facilitate the purification of compounds... Reagents that facilitate the purification of compounds...

B - Operations, Transporting

01

J

B01J 8/04 (2006.01) C07B 61/00 (2006.01) C07H 21/00 (2006.01) C07H 21/04 (2006.01) C08B 37/00 (2006.01)

Patent

CA 2458393

Disclosed is a novel capping-and-tagging ("cap-tag") strategy that aids in the purification of compounds assembled by multi-step synthetic methods. The incorporation of a unique cap-tag into undesired intermediates during a multi- step synthesis allows for the straightforward removal of these undesired compounds at the conclusion of the synthetic protocol by several methods based on affinity chromatography and scavenging resins. Importantly, this invention may be exploited in any automated synthetic protocol. In preferred embodiments, the cap-tag system is exploited for the purification of carbohydrates prepared via automated solid-phase methods.

La présente invention concerne une nouvelle stratégie de coiffage et de marquage ( 'coiffe-marque'') qui facilite la purification de composés assemblés au moyen de procédés de synthèse en plusieurs étapes. L'incorporation d'une coiffe-marque unique dans des intermédiaires indésirables pendant une synthèse en plusieurs étapes permet d'éliminer directement les composés indésirables à la fin du protocole de synthèse à l'aide de plusieurs procédés basés sur la chromatographie par affinité et des résines de piégeage. Il est important de noter que cette invention peut être utilisée dans n'importe quel protocole de synthèse automatisé. Dans les formes de réalisation préférées, le système coiffe-marque est utilisé pour purifier des hydrates de carbone préparés au moyen de procédés automatisés en phase solide.

Affiliated with

Also associated with

Rating

Reagents that facilitate the purification of compounds... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Reagents that facilitate the purification of compounds..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Reagents that facilitate the purification of compounds... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1444297