Real time detection of antigens

G - Physics – 01 – N

Patent

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Details

G01N 33/543 (2006.01) G01N 33/53 (2006.01) G01N 33/544 (2006.01) G01N 33/552 (2006.01)

Patent

CA 2328249

A modified bead having a structure represented by the formula B-X-A is disclosed, wherein B is a solid support preferably in the form of a bead, X is a spacer selected from the group consisting of poly(threonine), poly(serine), dextran, and poly(ethylene glycol), and A is an antibody. Using such modified beads in an immunoflow module, antigens can be captured and detected from food and environmental samples in about 30 minutes.

L'invention concerne une perle modifiée présentant une structure désignée par la formule B-X-A, dans laquelle B est un support solide de préférence sous la forme d'une perle, X est un bras espaceur choisi dans le groupe composé par la poly(thréonine), la poly(sérine), le dextrane, et le polyéthylèneglycol, et A est un antigène. En utilisant ces perles modifiées dans un module d'écoulement immunologique, on peut détecter et capturer les antigènes dans des échantillons d'aliments et dans des échantillons prélevés dans l'environnement, en approximativement 30 minutes.

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